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Oocyte donation in Spain is regulated by the Law n. 14/2006 of May 26th about Assisted Human Reproduction Techniques and by the Royal Decree 1301/2006, both derive from the European directives 2004/23/CE, 2006/17//CE and 2006/86/CE regarding the donation of human tissues and cells.


The Institute for Reproductive Medicine (IMER) is recognized by the EU and by the Spanish health authorities as an authorized center for the storage, manipulation and transfer of gametes and embryos to other clinics in Spain and other EU countries, that require them to perform medically assisted reproduction treatments.


Oocyte donation is a voluntary, altruistic and anonymous act, therefore receiving patients are not allowed to bring or select the oocyte donor. Choosing the most compatible donor is the sole responsibility of the medical team following the treatment. All the effort will be made to obtain the maximum possible immunological and phenotypic compatibility of the donated oocytes with the receiving patients. Receiving patients and their descendants have the right to request general information about their donor, but not the identity.


IMERbiobank’s oocyte donors are women aged from 18 to 28 years, resident in Spain, that have undertaken rigorous and comprehensive medical and psychological tests. They do not have hereditary diseases and at the time of donation they are free from infectious diseases.


According to Spanish law on assisted reproduction, the maximum number of children born from the oocytes donated by the same donor, cannot be more than six.





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Our oocyte donors are people fully capable of understanding and willing, with good health condition and with negative history of hereditary diseases and genetic abnormalities in their family. Following is a list of the performed tests:


  • Psychological assessment. Through a detailed personal interview led by our team of psychologists, we discard the existence of psychiatric, psychological disorders or inadequate habits.

  • Clinical history and medical visit to assess the personal and family history of the donor.

  • Hormonal study to find out ovarian function and complete gynecological examination with cytology.

  • Karyotype: assessment of chromosomal and genetic normality. Study of the 50 mostly relevant mutations of the gene for cystic fibrosis and genetic study to rule out the fragile X mutation syndrome.

  • Vaginal and cervical tampon with search for Neisseria Gonorrhoeae, Mycoplasma Hominis, Ureaplasma Urealyticum and Chlamydia Trachomatis.

  • Blood group and Rh factor.

  • Biochemical Profile, full CBC and study of blood coagulation.

  • Serological Analytics to rule out the possibility that donors are carriers of infectious diseases::



  • Hepatitis B  with nucleic amplification PRC (HBV-NAT)

  • Hepatitis C  with nucleic amplification PRC (HCV-NAT)

  • AIDS with nucleic amplification PRC (HIV-NAT)

  • Syphilis (TPHA-VDRL)

  • Ab anti- Cytomegalovirus IgG, IgM

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