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Sperm donation in Spain is regulated by the Law n. 14/2006 of May 26th about Assisted Human Reproduction Techniques and by the Royal Decree 1301/2006, both derive from the European directives 2004/23/CE, 2006/17//CE and 2006/86/CE regarding the donation of human tissues and cells.


 The Institute for Reproductive Medicine (IMER) is recognized by the EU and by the Spanish health authorities as an authorized center for the storage, manipulation and transfer of gametes and embryos to other clinics in Spain and other EU countries, that require them to perform medically assisted reproduction treatments.


Sperm donation is a voluntary, altruistic and anonymous act, therefore receivers patients are not allowed to bring or select the sperm donor. Choosing the most compatible donor is the sole responsibility of the medical team following for treatment. All the effort will be made to obtain the maximum possible immunological and phenotypic compatibility of the donated oocytes with the receiving patients. Receiving patients and their descendants have the right to request general information about their donor, but not the identity.


IMERbiobank’s donors are men aged between 18 and 35 years, resident in Spain, that have undertaken rigorous and comprehensive medical and psychological tests. They do not have hereditary diseases and at the time of donation they are free from infectious diseases.


According to Spanish law on assisted reproduction, the maximum number of children born from the sperm donated by the same donor, cannot be more than six.

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Our sperm donors are people fully capable of understanding and willing, with good health condition and with negative history of hereditary diseases and genetic abnormalities in their family. Following is a list of the performed tests:


  • Psychological assessment.

  • Clinical history and medical visits to assess personal and family history of the donor.

  • Karyotype: assessment of chromosomal and genetic normality. Study of the 50 mostly relevant mutations of the gene for cystic fibrosis and genetic study to rule out the fragile X mutation syndrome.

  • Semen culture, urine culture, search for Neisseria Gonorrhoeae, Mycoplasma Hominis, Ureaplasma Urealyticum and Chlamydia Trachomatis.

  • Blood group and Rh factor.

  • Biochemical Profile, full CBC and study of blood coagulation.

  • Serological Analytics to rule out the possibility that donors are carriers of infectious diseases:


  • Hepatitis B (HbsAg)

  • Hepatitis C (Ab anti HCVAb)

  • AIDS (HIV 1/2 ab IV generation and Ag p24 del VIH-1)

  • Syphilis (TPHA-VDRL)

  • Ab anti- Cytomegalovirus IgG, IgM


QUARANTINE OF SEMEN: Blood tests are performed for each donation, if these are performed in a period higher than 90 days. Samples of donated sperm are quarantined for a minimum of 180 days, after which analytics are repeated. If the negativity of the disease is confirmed, the samples are approved for donation.

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